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KMID : 0359320130530030177
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Korean Journal of Veterinary Research
2013 Volume.53 No. 3 p.177 ~ p.180
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Flurbiprofen toxicity in 2 dogs
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Lee Ye-Hyun
Nam Eui-Hwa
Park Seol-Hee
Song Chi-Youn
Lee Yong-Uk
Lee Jong-Myung
Park Jung-Hoon
Hwang Cheol-Young
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Abstract
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Two dogs were presented with melena, vomiting and depression after accidental swallowing of candy form of Strepsils (flurbiprofen), which is one of non-steroidal anti-inflammatory drugs used in human medicine for controlling a sore throat. These dogs had common signs of anemia induced by gastrointestinal ulceration and hemorrhage with azotemia and leukocytosis. The dogs were treated with blood transfusion, fluid therapy, proton-pump inhibitor, antiemetics, mucus protectant and antibiotic. Although most of clinical signs of two dogs were resolved, azotemic problem with evidence of renal injury have remained.
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KEYWORD
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dogs, non-steroidal anti-inflammatory drugs (NSAIDs), Strepsils (flurbiprofen), toxicity
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